IRE1α protects against osteoarthritis by regulating progranulin-dependent XBP1 splicing and collagen homeostasis
Abstract Osteoarthritis (OA) is a full-joint, multifactorial, degenerative and inflammatory disease that seriously affects the quality of life of patients due to its disabling and pain-causing properties. ER stress has been reported to be closely related to the progression of OA. The inositol-requir...
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| Автори: | , , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Publishing Group
2023-11-01
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| Серія: | Experimental and Molecular Medicine |
| Онлайн доступ: | https://doi.org/10.1038/s12276-023-01106-w |
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