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Platelet activation through CD62P and the formation of platelet–monocyte complexes are associated with the exacerbation of mucosal inflammation in patients with ulcerative colitis

Abstract Ulcerative colitis (UC) is a refractory, chronic inflammatory bowel disease of unknown etiology. Although platelets are activated in UC, their relevance in pathophysiology remains unclear. We analyzed the correlation of platelet activation and platelet–monocyte complexes (PMCs) with severit...

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Hlavní autoři: Yasuki Sano, Takashi Tomiyama, Naoto Yagi, Yuka Ito, Yusuke Honzawa, Tomomitsu Tahara, Tsukasa Ikeura, Toshiro Fukui, Shinji Shimoda, Makoto Naganuma
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-11-01
Edice:Scientific Reports
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On-line přístup:https://doi.org/10.1038/s41598-024-78462-8
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