Clinical implications of recurrent gene mutations in acute myeloid leukemia

Abstract Acute myeloid leukemia (AML) is a genetically heterogeneous clonal malignancy characterized by recurrent gene mutations. Genomic heterogeneity, patients’ individual variability, and recurrent gene mutations are the major obstacles among many factors that impact treatment efficacy of the AML...

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Hlavní autoři:	Jifeng Yu, Yingmei Li, Danfeng Zhang, Dingming Wan, Zhongxing Jiang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2020-03-01
Edice:	Experimental Hematology & Oncology
Témata:	Recurrent gene mutation Acute myeloid leukemia (AML) FLT3 CEBPA NPM1 RUNX1
On-line přístup:	http://link.springer.com/article/10.1186/s40164-020-00161-7
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