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Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates

Buprenorphine plays a crucial role in the therapeutic management of pain in adults, adolescents and pediatric subpopulations. However, only few pharmacokinetic studies of buprenorphine in children, particularly neonates, are available as conducting clinical trials in this population is especially ch...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lukas Kovar, Christina Schräpel, Dominik Selzer, Yvonne Kohl, Robert Bals, Matthias Schwab, Thorsten Lehr
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2020-06-01
Cyfres:Pharmaceutics
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/1999-4923/12/6/578
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!