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Single-Cell Landscape of Mouse Islet Allograft and Syngeneic Graft

Islet transplantation to treat the late stage of type 1 diabetic patient (T1DM) has recently made inspiring success in clinical trials. However, most patients experience a decline in islet graft function in one to three years due to immune rejection. Although the mechanisms of immune cells, includin...

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Principais autores: Pengfei Chen, Fuwen Yao, Ying Lu, Yuanzheng Peng, Shufang Zhu, Jing Deng, Zijing Wu, Jiao Chen, Kai Deng, Qi Li, Zuhui Pu, Lisha Mou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-06-01
coleção:Frontiers in Immunology
Assuntos:
the immune atlas
allograft
single-cell RNA sequencing
immune heterogeneity
islet
Beta cell
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.853349/full
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