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Caffeine extends lifespan by enhancing lysosomal lipolysis in Caenorhabditis elegans

ABSTRACT: Caffeine is a globally consumed stimulant that has beneficial effects on biological processes, including metabolism and aging, but its causal role in physiology remains incompletely understood. By using the roundworm Caenorhabditis elegans, here we show that caffeine extends lifespan by en...

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Principais autores: Hyemin Min, Eunseok Kang, Gee-Yoon Lee, Laura Bahr, Arjumand Ghazi, Seung-Jae V. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-06-01
coleção:Molecules and Cells
Assuntos:
Caenorhabditis elegans
Caffeine
Dietary restriction
Lipolysis
Longevity
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S101684782600049X
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