Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation

Abstract Rheumatoid arthritis (RA) is characterized by bone destruction in the afflicted joints, and during the process of bone destruction, osteoclasts play a crucial role. Tanshinone IIA (Tan IIA) has shown anti-inflammatory effects in RA. However, the exact molecular mechanisms by which it delays...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Qiuwei Peng, Jian Wang, Man Han, Minghong Zhao, Kesong Li, Tianming Lu, Qiuyan Guo, Quan Jiang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2023-05-01
Σειρά:	Chinese Medicine
Θέματα:	Tanshinone IIA Rheumatoid arthritis Osteoclast Lactate dehydrogenase Reactive oxygen species
Διαθέσιμο Online:	https://doi.org/10.1186/s13020-023-00765-1
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