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A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii

Cytidine triphosphate synthase catalyzes the synthesis of cytidine 5′-triphosphate (CTP) from uridine 5′-triphosphate (UTP), the final step in the production of cytidine nucleotides. CTP synthases also form filamentous structures of different morphologies known as cytoophidia, whose functions in mos...

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Principais autores: Heidy Y. Narvaez-Ortiz, Andrea J. Lopez, Nishith Gupta, Barbara H. Zimmermann
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-03-01
coleção:Frontiers in Cellular and Infection Microbiology
Assuntos:
Toxoplasma gondii
CTP synthase
pyrimidine
nucleotide biosynthesis
cytoophidium
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00083/full
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