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Comparison of efficacy, safety, immune response of dNS1 LAIV and cold-adapted LAIV in a mouse model

Abstract Influenza remains a significant global public health concern. Live-attenuated influenza vaccines (LAIVs) are recognized as effective interventions for influenza prevention. Currently, two types of LAIVs are licensed for human use: one developed through cold-adapted viral gene mutation and t...

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Autors principals: Xijing Wang, Xu Zhang, Congjie Chen, Heming Chen, Yaode Chen, Ruotong Wu, Xiangjie Chen, Zhen Lu, Ningshao Xia, Junyu Chen, Yixin Chen
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-12-01
Col·lecció:npj Vaccines
Accés en línia:https://doi.org/10.1038/s41541-025-01320-9
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