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Activation of human complement system by dextran-coated iron oxide nanoparticles is not affected by dextran/Fe ratio, hydroxyl modifications and crosslinking

While having tremendous potential as therapeutic and imaging tools, the clinical use of engineered nanoparticles has been associated with serious safety concerns. Activation of the complement cascade and release of proinflammatory factors C3a and C5a may contribute to infusion-related reactions, whe...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Guankui Wang, Fangfang Chen, Nirmal Banda, VM Holers, Linping Wu, Moein Moghimi, Dmitri Simberg
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2016-10-01
Rangatū:Frontiers in Immunology
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00418/full
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