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Biphasic adaptation of gBOLD-CSF coupling during sleep deprivation reflects compensatory enhancement and temporal disruption in glymphatic function

Sleep deprivation (SD) significantly impacts brain function, particularly through disruption of the glymphatic system, an essential mechanism for cerebral metabolic waste clearance dependent on cerebrospinal fluid (CSF) dynamics. Recent advances link CSF flow to global brain activity, measurable via...

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Principais autores: Dai Zhang, Rong Wang, Liqin Zhou, Ke Zhou, Zhentao Zuo, Guochen Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-03-01
coleção:NeuroImage
Assuntos:
Sleep deprivation
Glymphatic system
Cerebrospinal fluid
Resting-state fMRI
Brain metabolic clearance
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S105381192600087X
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