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PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells.

The Prion Protein (PrP) is an ubiquitously expressed glycosylated membrane protein attached to the external leaflet of the plasma membrane via a glycosylphosphatidylinositol anchor (GPI). While the misfolded PrPSc scrapie isoform is the infectious agent of prion disease, the cellular isoform (PrPC)...

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Bibliografische Detailangaben
Hauptverfasser: Alexander Arkhipenko, Sylvie Syan, Guiliana Soraya Victoria, Stéphanie Lebreton, Chiara Zurzolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2016-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC4936696?pdf=render
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