Rohitukine inhibits in vitro adipogenesis arresting mitotic clonal expansion and improves dyslipidemia in vivo[S]

We developed a common feature pharmacophore model using known antiadipogenic compounds (CFPMA). We identified rohitukine, a reported chromone anticancer alkaloid as a potential hit through in silico mapping of the in-house natural product library on CFPMA. Studies were designed to assess the antiadi...

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Autors principals:	Salil Varshney, Kripa Shankar, Muheeb Beg, Vishal M. Balaramnavar, Sunil Kumar Mishra, Pankaj Jagdale, Shishir Srivastava, Yashpal S. Chhonker, Vijai Lakshmi, Bhushan P. Chaudhari, Rabi Shankar Bhatta, Anil Kumar Saxena, Anil Nilkanth Gaikwad
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2014-06-01
Col·lecció:	Journal of Lipid Research
Matèries:	S-phase arrest Dysoxylum binacteriferum Hook. f 3T3-L1 C3H10T1/2
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0022227520352664
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