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Inhibition of miR-33a-5p in Macrophage-like Cells In Vitro Promotes apoAI-Mediated Cholesterol Efflux

Atherosclerosis is caused by cholesterol accumulation within arteries. The intima is where atherosclerotic plaque accumulates and where lipid-laden foam cells reside. Intimal foam cells comprise of both monocyte-derived macrophages and macrophage-like cells (MLC) of vascular smooth muscle cell (VSMC...

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Principais autores: Olanrewaju Oladosu, Emma Chin, Christian Barksdale, Rhonda R. Powell, Terri Bruce, Alexis Stamatikos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-02-01
coleção:Pathophysiology
Assuntos:
aortic smooth muscle cell
cardiovascular disease
immortalized cell line
reverse cholesterol transport
shRNA
trans-differentiation
Acesso em linha:https://www.mdpi.com/1873-149X/31/1/9
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