HETEROSUBTYPIC IMMUNE RESPONSE AND CROSS-PROTECTION AGAINST A HIGHLY PATHOGENIC A (H5N1) INFLUENZA VIRUS IN MICE IMMUNIZED WITH COLD-ADAPTED A/LENINGRAD/134/17/57 (H2N2) INFLUENZA VIRUS

While investigating the efficacy of an H5N2 ca reassortant vaccine candidate in protecting against a lethal challenge with a highly pathogenic (HP) H5N1 virus in the mouse model, we observed a degree of cross-protection provided by the ca Len/17 (H2N2) virus itself. 80% of mice administered a high d...

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Detalhes bibliográficos

Principais autores:	A. R. Rekstin, J. A. Desheva, X. Lu, G. I. Alexandrova, A. I. Klimov, J. M. Katz, L. G. Rudenko
Formato:	Artigo
Idioma:	Russo
Publicado em:	St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Colecção:	Медицинская иммунология
Assuntos:	heterosubtypic immunity live influenza vaccine avian influenza viruses
Acesso em linha:	http://mimmun.ru/index.php/mimmun/article/view/598
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