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UBX‐390: A Novel Androgen Receptor Degrader for Therapeutic Intervention in Prostate Cancer

Abstract The androgen receptor (AR) is an attractive target for treating prostate cancer, considering its role in the development and progression of localized and metastatic prostate cancer. The high global mortality burden of prostate cancer, despite medical treatments such as androgen deprivation...

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Principais autores: Soohyun Lee, Hwa‐Ryeon Kim, Yaejin Woo, Jiyoung Kim, Han Wool Kim, Ji Youn Park, Beomseon Suh, Yuri Choi, Jungmin Ahn, Je Ho Ryu, Jae‐Seok Roe, Jaewhan Song, Song Hee Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2024-09-01
coleção:Advanced Science
Assuntos:
androgen receptor
cancer therapy
degrader
prostate cancer
PROTAC
Acesso em linha:https://doi.org/10.1002/advs.202400398
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