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Improved analysis of in vivo drug combination experiments with a comprehensive statistical framework and web-tool

Abstract Drug combination therapy is often required to overcome the limited benefits of monotherapy in cancer treatment. While several tools exist for in vitro drug synergy screening and assessment, there is a lack of integrated methods for statistical analysis of in vivo combination experiments. To...

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Auteurs principaux: Rafael Romero-Becerra, Zhi Zhao, Daniel Nebdal, Elisabeth Müller, Helga Bergholtz, Jens Henrik Norum, Tero Aittokallio
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-11-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-025-65218-9
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