Mitochondrial proteomics reveals reductive metabolism dependent on glutamine in fibroblasts of idiopathic pulmonary fibrosis under hypoxia

Abstract Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), is a chronic disease characterized not only by a transcriptionally active signature associated with hypoxia but also by feedback loops that may underlie disease progression. IPF fibroblasts are known to contribute to dise...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yair Romero, Manuel Castillejos-López, Erika Rubí Luis-Garcia, Adriana Becerra-Cervera, Diana I. Aparicio-Bautista, Iliana Herrera, Víctor Ruiz, Emmanuel Ríos-Castro, Carina Becerril, Nayeli Torres-Ramírez, Rosario Ortiz-Hernández, Jose Cisneros, Ana Karen Torres-Soria, Joaquin Zuñiga, Edgar Flores-Soto, Yalbi Itzel Balderas-Martinez, Ángeles Carlos-Reyes, Luz María Torres-Espíndola, Rafael Velázquez-Cruz, Arnoldo Aquino-Gálvez
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2026-01-01
Sarja:	Scientific Reports
Aiheet:	IPF Mitochondria Lung fibroblasts Proteome
Linkit:	https://doi.org/10.1038/s41598-025-26911-3
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