​The inverse relationship between copy number variation burden and age of onset of metabolic syndrome in Korean middle-aged adults

Abstract Background Metabolic syndrome (MetS) shows wide inter-individual variation in age at onset, yet the contribution of structural genomic variation is underexplored. We posited that copy number variation (CNV) burden—an aggregate of autosomal deletions and duplications—anticipates the timing o...

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Hauptverfasser:	Seong-Hee Ko, Minyeong Kim, Dayeon Shin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-04-01
Schriftenreihe:	BMC Medical Genomics
Schlagworte:	Copy number variations Metabolic syndrome Onset ages Genome-wide association study Korean Genome and Epidemiology Study (KoGES)
Online-Zugang:	https://doi.org/10.1186/s12920-026-02353-2
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