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Long-term safety of canakinumab in patients with systemic juvenile idiopathic arthritis: 5-year results from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry

Abstract Background Systemic juvenile idiopathic arthritis (SJIA) is a severe form of juvenile idiopathic arthritis characterized by fever, rash, chronic arthritis, and systemic inflammation. The introduction of biologics has improved the treatment options for SJIA. Canakinumab selectively inhibits...

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Autori principali: Colleen Correll, Alis Burciu, Amita Bansal, Anne Dennos, Deepak Narayanswamy, Elodie Aubrun, Laura E. Schanberg, Li Yuhan, Rahel Schneider, Stephen Balevic, Yukiko Kimura, Timothy Beukelman, for the CARRA Registry investigators
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-10-01
Serie:Pediatric Rheumatology Online Journal
Soggetti:
Systemic juvenile idiopathic arthritis
Canakinumab
CARRA registry
Safety
Accesso online:https://doi.org/10.1186/s12969-025-01144-w
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