Stem cell-derived exosomes prevent the development of thoracic aortic aneurysm/dissection by inhibiting AIM2 inflammasome and pyroptosis

Thoracic aortic aneurysm/dissection (TAAD) is a severe vascular condition associated with life-threatening complications, and its underlying molecular mechanisms remain largely unexplored. Previous research indicates that the aberrant activation of cytosolic DNA and its receptors plays a crucial rol...

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Detalhes bibliográficos

Principais autores:	Lin Lu, Feng Liu, Weiliang Wu, Yu Zhang, Bin Liu, Qingfang Han, Tonggan Lu, Huiling Zhang, Xi-yong Yu, Yangxin Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-12-01
Colecção:	Extracellular Vesicle
Assuntos:	AIM2 Thoracic aortic aneurysm/dissection Inflammation Deubiquitinating enzymes Exosome
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2773041724000131
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