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BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

<p>Abstract</p> <p>Background</p> <p>Basal-like breast cancers (BLBC) are aggressive breast cancers for which, so far, no targeted therapy is available because they typically lack expression of hormone receptors and HER2. Phenotypic features of BLBCs, such as clinical presentation and early age of o...

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Auteurs principaux: van de Vijver Marc J, Børresen-Dale Anne-Lise, Langerød Anita, Velds Arno, Horlings Hugo M, Holstege Henne, Nederlof Petra M, Jonkers Jos
Format: Artigo
Langue:Inglês
Publié: BMC 2010-11-01
Collection:BMC Cancer
Accès en ligne:http://www.biomedcentral.com/1471-2407/10/654
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