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FXYD5/Dysadherin, a Biomarker of Endometrial Cancer Myometrial Invasion and Aggressiveness: Its Relationship With TGF-β1 and NF-κB Pathways

Objective: Endometrial cancer (EC) is the second most common gynecological cancer worldwide. Myometrial invasion (MI) is a key event in EC dissemination. This study aimed to evaluate FXYD5/dysadherin (FXYD5/Dys) expression in EC tissue and uterine aspirate (UA) biopsies and to assess molecular/funct...

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Principais autores: María José Besso, Marina Rosso, Lara Lapyckyj, Cristian Pablo Moiola, María Laura Matos, María Florencia Mercogliano, Roxana Schillaci, Jaume Reventos, Eva Colas, Antonio Gil-Moreno, Alejandra Wernicke, Roberto Orti, Mónica Hebe Vazquez-Levin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-12-01
Serier:Frontiers in Oncology
Fag:
endometrial cancer
E-cadherin
FXYD5
dysadherin
TGF-β1
NF-κB
Online adgang:https://www.frontiersin.org/article/10.3389/fonc.2019.01306/full
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