sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's disease

Abstract Microglial activation occurs early in Alzheimer's disease (AD) and previous studies reported both detrimental and protective effects of microglia on AD progression. Here, we used CSF sTREM2 to investigate disease stage‐dependent drivers of microglial activation and to determine downstream c...

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Bibliografische Detailangaben

Hauptverfasser:	Davina Biel, Marc Suárez‐Calvet, Paul Hager, Anna Rubinski, Anna Dewenter, Anna Steward, Sebastian Roemer, Michael Ewers, Christian Haass, Matthias Brendel, Nicolai Franzmeier, for the Alzheimer's Disease Neuroimaging Initiative (ADNI)
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Springer Nature 2023-01-01
Schriftenreihe:	EMBO Molecular Medicine
Schlagworte:	Alzheimer's disease beta‐amyloid glucose metabolism p‐tau sTREM2
Online-Zugang:	https://doi.org/10.15252/emmm.202216987
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