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Circular RNA circCSPP1 knockdown attenuates doxorubicin resistance and suppresses tumor progression of colorectal cancer via miR-944/FZD7 axis

Abstract Background Circular RNAs (circRNAs) have been reported to play vital roles in colorectal cancer (CRC). However, only a few circRNAs have been experimentally validated and functionally described. In this research, we aimed to reveal the functional mechanism of circCSPP1 in CRC. Methods 36 DO...

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Principais autores: Lanlan Xi, Quanlin Liu, Wei Zhang, Linshan Luo, Jingfeng Song, Ruitao Liu, Shue Wei, Yong Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-03-01
Serier:Cancer Cell International
Fag:
CircCSPP1
MiR-944
FZD7
DOX-resistant
Tumor progression
Colorectal cancer
Online adgang:https://doi.org/10.1186/s12935-021-01855-6
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