Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC‐3G3) to patients with advanced soft tissue sarcoma

Abstract Background Olaratumab, a fully human monoclonal antibody, selectively binds to human platelet‐derived growth factor receptor alpha and blocks ligand binding. This study assessed the effect of olaratumab on the pharmacokinetics (PK) of doxorubicin and the safety of olaratumab alone and in co...

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Bibliographic Details

Main Authors:	Victor M. Villalobos, Gary Mo, Mark Agulnik, Seth M. Pollack, Daniel A. Rushing, Arun Singh, Brian A. Van Tine, Rhian McNaughton, Rodney L. Decker, Wei Zhang, Ashwin Shahir, Damien M. Cronier
Format:	Artigo
Language:	Inglês
Published:	Wiley 2020-02-01
Series:	Cancer Medicine
Subjects:	doxorubicin monoclonal antibody olaratumab pharmacokinetics soft tissue sarcoma
Online Access:	https://doi.org/10.1002/cam4.2728
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