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The effects of quercetin on seizure, inflammation parameters and oxidative stress in acute on chronic tramadol intoxication

Abstract Background Tramadol is a widely used synthetic opioid for moderate to severe pain. Some studies have shown that tramadol can increase oxidative stress in different tissues of the body. Quercetin is also a substance with various biological effects, including antioxidant, anti-inflammatory, h...

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Main Authors: Samaneh Nakhaee, Khadijeh Farrokhfall, Ebrahim Miri-Moghaddam, Mohsen Foadoddini, Masoumeh Askari, Omid Mehrpour
Format: Artigo
Language:Inglês
Published: BMC 2021-10-01
Series:BMC Pharmacology and Toxicology
Subjects:
Acute on chronic
Inflammation
Oxidative stress
Quercetin
Tramadol
Online Access:https://doi.org/10.1186/s40360-021-00532-8
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