Dynamic gut microbiota changes in patients with advanced malignancies experiencing secondary resistance to immune checkpoint inhibitors and immune-related adverse events

BackgroundImmune checkpoint inhibitors (ICIs) have been a breakthrough in cancer immunotherapy, but secondary resistance (SR) and immune-related adverse events (irAEs) are significant clinical dilemmas. Although the gut microbiota is associated with ICI efficacy and irAEs, the knowledge of longitudi...

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Hlavní autoři:	Yanlin Zeng, Qingya Shi, Xinyu Liu, Hao Tang, Bo Lu, Qingyang Zhou, Yan Xu, Minjiang Chen, Jing Zhao, Yue Li, Jiaming Qian, Mengzhao Wang, Bei Tan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-04-01
Edice:	Frontiers in Oncology
Témata:	gut microbiota lung cancer immune checkpoint inhibitor immune-related adverse event secondary resistance
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1144534/full
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