Integrative metagenomic and metabolomic analysis reveals a gut microbiota-metabolite-immune axis in pediatric allergic rhinitis with functional constipation

ObjectiveThis study aimed to delineate the alterations in the gut microbiome and host amino acid metabolism in children with comorbid allergic rhinitis and functional constipation (ARFC), and to explore their links with clinical allergy markers.MethodsWe performed shotgun metagenomic sequencing and...

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Hlavní autoři:	Hui Wu, Lindong Shi, Chunyan Wang, Yushan Liang, Congfu Huang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-05-01
Edice:	Frontiers in Cellular and Infection Microbiology
Témata:	allergic rhinitis amino acids functional constipation gut microbiota metagenomics microbiota-metabolite axis
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcimb.2026.1779298/full
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