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Necdin modulates proliferative cell survival of human cells in response to radiation-induced genotoxic stress

<p>Abstract</p> <p>Background</p> <p>The finite replicative lifespan of cells, termed cellular senescence, has been proposed as a protective mechanism against the proliferation of oncogenically damaged cells, that fuel cancer. This concept is further supported by the induction of premature senescenc...

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Principais autores: Lafontaine Julie, Tchakarska Guergana, Rodier Francis, Mes-Masson Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2012-06-01
Series:BMC Cancer
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Acceso en liña:http://www.biomedcentral.com/1471-2407/12/234
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