Clinical aspects of TP53 gene inactivation in diffuse large B-cell lymphoma

Abstract Background The knowledge about specific mechanisms generating TP53 dysfunction in diffuse large B-cell lymphoma is limited. The aim of the current study was to comprehensively explore TP53 gene variability resulting from somatic mutations, promoter methylation, and allelic imbalance in tumo...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Elena N. Voropaeva, Tatyana I. Pospelova, Mikhail I. Voevoda, Vladimir N. Maksimov, Yuriy L. Orlov, Olga B. Seregina
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2019-03-01
Цуврал:	BMC Medical Genomics
Нөхцлүүд:	TP53 gene Diffuse large B-cell lymphoma Methylation Allelic imbalance Intron mutations Sequencing
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12920-019-0484-9
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!