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Structure of a classical MHC class I molecule that binds "non-classical" ligands.

Chicken YF1 genes share a close sequence relationship with classical MHC class I loci but map outside of the core MHC region. To obtain insights into their function, we determined the structure of the YF1*7.1/β(2)-microgloblin complex by X-ray crystallography at 1.3 Å resolution. It exhibits the arc...

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Principais autores: Chee Seng Hee, Song Gao, Bernhard Loll, Marcia M Miller, Barbara Uchanska-Ziegler, Oliver Daumke, Andreas Ziegler
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Biology
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151886/?tool=EBI
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