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All-trans retinoic acid inhibits glioblastoma progression and attenuates radiation-induced brain injury

Radiotherapy (RT) remains a primary treatment modality for glioblastoma (GBM), but it induces cellular senescence and is strongly implicated in GBM progression and RT-related injury. Recently, eliminating senescent cells has emerged as a promising strategy for treating cancer and for mitigating radi...

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Principais autores: Min Fu, Yiling Zhang, Bi Peng, Na Luo, Yuanyuan Zhang, Wenjun Zhu, Feng Yang, Ziqi Chen, Qiang Zhang, Qianxia Li, Xin Chen, Yuanhui Liu, Guoxian Long, Guangyuan Hu, Xiaohong Peng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2024-11-01
Serier:JCI Insight
Fag:
Aging
Online adgang:https://doi.org/10.1172/jci.insight.179530
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