HTGTS‐TCR‐Seq for Profiling of Mouse and Human T‐Cell Receptor α and β Gene Rearrangements and Diversity

Abstract Developing αβ T lymphocytes generate T‐cell receptor (TCR) diversity through V(D)J recombination, which assembles Tcra and Tcrb genes from germline variable (V), diversity (D), and joining (J) segments. Approaches to characterize TCR rearrangements and diversity are critical for studying T‐...

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Bibliographic Details

Main Authors:	Rui Luo, Yawei Song, Meichen Wang, Longhao Zou, Fangtai Jiao, Tiange Yang, Guangchuan Wang, Zhuoyi Liang, Wei Wu, Hai‐Qiang Dai
Format:	Artigo
Language:	Inglês
Published:	Wiley 2026-01-01
Series:	Advanced Science
Subjects:	αβ T cells antigen receptor diversification TCR repertoire HTGTS‐TCR‐seq V(D)J recombination
Online Access:	https://doi.org/10.1002/advs.202509497
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