Use of osteoblast-derived matrix to assess the influence of collagen modifications on cancer cells

Collagenous stromal accumulations predict a worse clinical outcome in a variety of malignancies. Better tools are needed to elucidate the way in which collagen influences cancer cells. Here, we report a method to generate collagenous matrices that are deficient in key post-translational modification...

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Hlavní autoři:	Neus Bota-Rabassedas, Hou-Fu Guo, Priyam Banerjee, Yulong Chen, Masahiko Terajima, Mitsuo Yamauchi, Jonathan M. Kurie
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2020-11-01
Edice:	Matrix Biology Plus
Témata:	Collagen Collagen cross-links Co-culture models Lysyl hydroxylases Lung cancer Metastasis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2590028520300284
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