HRP2 and HRP3 cross-reactivity and implications for HRP2-based RDT use in regions with Plasmodium falciparum hrp2 gene deletions

Abstract Background The Plasmodium falciparum antigen histidine rich protein 2 (HRP2) is a preferred target for malaria rapid diagnostic tests (RDTs) because of its abundant production by the parasite and thermal stability. As a result, a majority of RDTs procured globally target this antigen. Howev...

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Bibliografische gegevens

Hoofdauteurs:	Amy Kong, Scott A. Wilson, Yong Ah, Douglas Nace, Eric Rogier, Michael Aidoo
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2021-04-01
Reeks:	Malaria Journal
Onderwerpen:	Malaria RDT HRP2 HRP3 Cross-reactivity Gene deletions
Online toegang:	https://doi.org/10.1186/s12936-021-03739-6
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