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An Ultrafast UPLC-MS/MS Approach for Determining the In Vitro Metabolic Stability of Duvelisib in the HLMs: In Silico Screening for Metabolic Lability, ADME Features, and DEREK Alerts

Duvelisib (COPIKTRA, Pfizer) is a prescription medication indicated for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have received at least two previous treatments that were ineffective or have ceased to be effective. This paper outlines the creation and val...

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Principais autores: Mohamed W. Attwa, Awadh M. Ali, Ali S. Abdelhameed, Adnan A. Kadi
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-01-01
coleção:International Journal of Analytical Chemistry
Acesso em linha:http://dx.doi.org/10.1155/ianc/9508534
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