Ascorbic acid and microcirculation in cardiothoracic surgery: a pilot feasibility trial and matched cohort study

Abstract Background Ascorbic acid is an essential cofactor of catecholamine synthesis that increases capillary bed density and improves microcirculation perfusion. We hypothesized early ascorbic acid administration in cardiothoracic surgery would preserve the microcirculatory integrity and minimize...

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Principais autores:	Patrick M. Wieruszewski, Misty A. Radosevich, Scott D. Nei, Kianoush B. Kashani, Sarah E. Normand, Hartzell V. Schaff, Erica D. Wittwer
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-05-01
Series:	Journal of Cardiothoracic Surgery
Assuntos:	Vasoplegia Vasodilation Shock Vitamin C Cardiopulmonary bypass Microcirculation
Acceso en liña:	https://doi.org/10.1186/s13019-025-03486-8
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