EMCV VP2 degrades IFI16 through Caspase-dependent apoptosis to evade IFI16-STING pathway
Abstract Interferon (IFN)-γ inducible protein 16 (IFI16), a key DNA sensor, triggers downstream STING-dependent type I interferon (IFN-I) production and antiviral immunity. However, how the IFI16-STING signaling pathway is regulated by EMCV infection is still not well elucidated. In this study, we i...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2024-11-01
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| Serie: | Virology Journal |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s12985-024-02568-8 |
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