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Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban by Andexanet Alfa as Measured by Whole Blood Thromboelastographic Analysis

Introduction The available oral anti-Xa agents are routinely used for the management of thrombotic disorders. A molecularly modified recombinant coagulation FXa, also known as Andexanet Alfa (AA), that has been developed as an antidote to neutralize the bleeding effects of oral FXa inhibitors, such...

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Główni autorzy: Siddharth Mehrotra, Debra Hoppensteadt PhD, Walter Jeske PhD, Fakiha Siddiqui BS, Omer Iqbal MD, Alfonso Tafur MD, Bruce Lewis MD, Mark Jaradeh BS, Bulent Kantarcioglu MD, Jawed Fareed PhD
Format: Artigo
Język:Inglês
Wydane: SAGE Publishing 2022-12-01
Seria:Clinical and Applied Thrombosis/Hemostasis
Dostęp online:https://doi.org/10.1177/10760296221138297
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