S-15176 Difumarate Salt Can Impair Mitochondrial Function through Inhibition of the Respiratory Complex III and Permeabilization of the Inner Mitochondrial Membrane

S-15176 difumarate salt, a derivative of the anti-ischemic metabolic drug trimetazidine, has been intensively studied for its impact on cellular metabolism in animal models of ischemia-reperfusion injury of the liver, heart, spinal cord, and other organs. Despite evidence of some reduction in oxidat...

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Bibliografische gegevens

Hoofdauteurs:	Natalia V. Belosludtseva, Vlada S. Starinets, Alena A. Semenova, Anastasia D. Igoshkina, Mikhail V. Dubinin, Konstantin N. Belosludtsev
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2022-02-01
Reeks:	Biology
Onderwerpen:	S-15176 mitochondria mitochondrial membrane potential mitochondrial respiration electron transport chain mitochondrial membrane permeabilization
Online toegang:	https://www.mdpi.com/2079-7737/11/3/380
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