A scalable Tn5-based method for genome-wide DNA methylation profiling in development and disease
Abstract DNA methylation is a key epigenetic modification involved in development and disease, including cancer, and serves as a biomarker for diagnosis. Current detection methods, such as bisulfite sequencing, provide base-pair resolution but require high sequencing depth and cost. Here, we develop...
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| Principais autores: | , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Nature Portfolio
2026-05-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/s41467-026-73325-4 |
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