In vitro and in vivo antimutagenic activity of Echinops spinosus crude extract and its aqueous fraction in mouse bone marrow and spleen

Abstract Background Echinops spinosus (ES), known as spiny globe thistle, has been widely used in traditional medicine to treat various ailments, such as splenic and renal disorders. However, the genoprotective effect of ES has not been examined previously. This report assessed the in vitro and in v...

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Hauptverfasser:	Kawthar A. Diab, Ayman A. Farghaly, Entesar E. Hassan, Maha A. Fahmy, Emad M. Hassan, Zeinab M. Hassan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-11-01
Schriftenreihe:	Genes and Environment
Schlagworte:	Echinops spinosus Ethyl methanesulfonate Genotoxicity; chromosomal aberration; comet assay Micronucleus Mice
Online-Zugang:	https://doi.org/10.1186/s41021-025-00341-z
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