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The immunoglobulin M-degrading enzyme of Streptococcus suis (Ide Ssuis ) leads to long-lasting inhibition of the activation of porcine IgM-secreting B cells

Abstract Streptococcus suis (S. suis) is one of the most important porcine pathogens, causing severe pathologies such as meningitis or polyarthritis. It is also a very successful colonizer of mucosal surfaces. The IgM-degrading enzyme of S. suis (Ide Ssuis ) specifically cleaves porcine IgM, which r...

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Principais autores: Annika Katharina Breitfelder, Wieland Schrödl, Christoph Georg Baums, Gottfried Alber, Uwe Müller
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-09-01
Serier:Veterinary Research
Fag:
Streptococcus suis
Ide Ssuis
IgM
B cell receptor
B cell receptor cleavage
ELISpot
Online adgang:https://doi.org/10.1186/s13567-024-01363-1
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