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Inflammation and Aging of Hematopoietic Stem Cells in Their Niche

Hematopoietic stem cells (HSCs) sustain the lifelong production of all blood cell lineages. The functioning of aged HSCs is impaired, including a declined repopulation capacity and myeloid and platelet-restricted differentiation. Both cell-intrinsic and microenvironmental extrinsic factors contribut...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Daozheng Yang, Gerald de Haan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-07-01
Schriftenreihe:Cells
Schlagworte:
Online-Zugang:https://www.mdpi.com/2073-4409/10/8/1849
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