5′-CMP and 5′-UMP alleviate dexamethasone-induced muscular atrophy in C2C12 myotubes

Atrogin-1 and muscle RING finger 1 (MuRF1) are ubiquitin ligases specifically expressed during skeletal muscle atrophy and mediate muscle protein degradation. In contrast, PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1α), which is a master regulator of mitochondrial biosynthesis,...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Kosuke Nakagawara, Chieri Takeuchi, Kazuya Ishige
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-07-01
coleção:	Biochemistry and Biophysics Reports
Assuntos:	Cytidine 5′-monophosphate Uridine 5′-monophosphate Nutrition Muscle atrophy E3 ubiquitin ligase PGC-1α
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405580823000419
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!