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Porous PLGA microspheres loaded with PTH1-34 peptide for long-term treatment of OA

Background: Osteoarthritis (OA) is a chronic disease characterized by degeneration of articular cartilage, affecting over 530 million patients worldwide. Current oral medications such as non-steroidal anti-inflammatory drugs (NSAIDs) can only alleviate symptoms and are associated with numerous adver...

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Autori principali: Wang Diaodiao, Tang Miaotian, Ren Pengcheng, Tian Zhuang, Zhang Gang, Liu Yubo, Sun Yuyang, Ye Peng, Sun Wenqiang, Yao Qi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2025-07-01
Serie:Journal of Orthopaedic Translation
Soggetti:
Osteoarthritis
PTH1-34
Porous PLGA microspheres
Sustained release
Cartilage repair
Accesso online:http://www.sciencedirect.com/science/article/pii/S2214031X25000804
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