Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice[S]

Low-grade inflammation in different tissues, including activation of the nuclear factor κB pathway in liver, is involved in metabolic disorders such as type 2 diabetes and cardiovascular diseases (CVDs). In this study, we investigated the relation between chronic hepatocyte-specific overexpression o...

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Detalhes bibliográficos

Principais autores:	Janna A. van Diepen, Man C. Wong, Bruno Guigas, Jasper Bos, Rinke Stienstra, Leanne Hodson, Steven E. Shoelson, Jimmy F.P. Berbée, Patrick C.N. Rensen, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2011-05-01
coleção:	Journal of Lipid Research
Assuntos:	nuclear factor kappa B lipid metabolism liver very low density lipoprotein IκB kinase β
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520408806
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