The role and regulatory mechanism of USP25 in pancreatic microcirculatory disturbance in severe acute pancreatitis

Abstract This study investigates the molecular mechanism by which USP25 contributes to pancreatic microcirculatory disturbance in severe acute pancreatitis (SAP). SAP was induced by retrograde injection of 4% sodium taurocholate into the pancreatic duct following adenoviral delivery of sh-USP25 to s...

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Hlavní autoři:	Qian Zhang, Xiao Zhang, Fei Shan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-03-01
Edice:	Scientific Reports
Témata:	Severe acute pancreatitis Microcirculatory disturbance USP25 Deubiquitination TRAF6
On-line přístup:	https://doi.org/10.1038/s41598-026-39295-9
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