Circulating plasma EBV DNA: a potential tool to facilitate diagnosis of pediatric Burkitt lymphoma in sub-Saharan Africa

Abstract: In sub-Saharan Africa (SSA), many pediatric patients with Burkitt lymphoma (BL) perish because of diagnostic delays. About 95% of pediatric BL cases in SSA are Epstein-Barr virus (EBV) positive. We assessed plasma EBV DNA in 400 pediatric patients with BL and 400 controls, frequency-matche...

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Principais autores:	Karena Volesky-Avellaneda, Rena R. Xian, Todd B. Young, Ryan N. Baugher, Martin D. Ogwang, Patrick Kerchan, Steven J. Reynolds, Constance N. Tenge, Pamela A. Were, Robert T. Kuremu, Walter N. Wekesa, Nestory Masalu, Esther Kawira, Stephanie D. Mellott, Heidi E. Lawhorn, Kristen M. Pike, Jennifer Stone, Laura Walsh, Tobias Kinyera, Isaac Otim, Hadijah Nabalende, Herry Dhudha, Leona W. Ayers, Kishor Bhatia, James J. Goedert, Daniel R. Soppet, Stephen M. Hewitt, Hyokyoung G. Hong, Richard F. Ambinder, Sam M. Mbulaiteye
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-12-01
Series:	Blood Global Hematology
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S3050565825000253
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